Dan Ashworth will leave his role as Manchester United sporting director after just five months.
Ashworth officially started his role on July 1 after a lengthy period of gardening leave at Newcastle, but now parts ways following Saturday's 3-2 home defeat to Nottingham Forest.
Ashworth was responsible for football performance and recruitment, reporting to new CEO Omar Berrada, who was hired from Manchester City.
The 53-year-old leaves Man Utd having overseen a £200m summer spend on Leny Yoro, Manuel Ugarte, Joshua Zirkzee, Matthijs de Light and Noussair Mazraoui.
During Ashworth's tenure, Erik ten Hag was sacked as Man Utd manager in October and replaced by Ruben Amorim - with it being reported at the time that Ashworth and Berrada led negotiations on appointing the Portuguese coach.
Ashworth also had successful spells at Brighton and the FA before Newcastle, and was seen as a statement appointment by minority owners INEOS, with Sir Jim Ratcliffe hailing him "one of the best sporting directors in the world".
A Man Utd statement said: "Dan Ashworth will be leaving his role as sporting director of Manchester United by mutual agreement.
"We would like to thank Dan for his work and support during a transitional period for the club and wish him well for the future."
